Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Dec 10;5:18037. doi: 10.1038/srep18037

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2015, Macmillan Publishers Limited

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

PMC Copyright notice

(A) The relationship of CM fractions and average methylation levels in normal tissues is shown in Table 1. The maximum CM and CM of random methylation trends were computed using simulated data of concordant and random methylation pattern (methylation levels from 0.1 to 0.9), respectively. (B) Probability density distribution of average CM fraction from cancer and normal tissues, respectively. (C) Occupancy rates of CMRs in promoter, 5′-UTR, exon, intron, 3′-UTR, DHS, CGI and CGS. Box figure represents the degree of difference in occupancy rate between cancer and normal cells in each region. Notably, the occupancy rate of CGI in cancer was more than 1 because the length of some CMRs in CGI was longer than the CGI. (D) Average values of CM fraction of cancer and normal cells in promoter, 5′-UTR, exon, intron, 3′-UTR, DHS, CGI and CGS. (E) The relationship between CM fractions and average methylation levels in normal and cancer cells, respectively. (F) Heat map of correlation of CM fraction or average methylation levels among tissues.