Table 1.
No. | Age | Sex | Aβ42 | HP-tau |
---|---|---|---|---|
1 | fetus (50 days) | F | − | +a |
2 | fetus (50 days) | M | − | +a |
3 | 2-week-old | F | − | − |
4 | 2-week-old | F | − | − |
5 | 3-year-old | M | − | − |
6 | 3-year-old | M | − | − |
7 | 4-year-old | F | − | − |
8 | 4-year-old | F | − | − |
9 | 5-year-old | F | − | − |
10 | 8-year-old | F | + | − |
11 | 14-year-old | F | − | − |
12 | 14-year-old | M | + | ++ |
13 | 15-year-old | F | + | + |
14 | 15-year-old | M | + | − |
15 | 15-year-old | ND | + | − |
16 | 16-year-old | F | + | − |
17 | 16-year-old | M | + | − |
18 | 17-year-old | F | + | − |
19 | 17-year-old | F | + | + |
20 | 17-year-old | ND | + | + |
21 | 18-year-old | F | + | + |
22 | 19-year-old | F | + | ++ |
23 | 20-year-old | F | + | + |
24 | 20-year-old | ND | + | ++ |
25 | 22-year-old | M | + | + |
Aβ42: -, negative; +, small aggregates of Aβ42 were observed in the parietal and temporal cortices on FA-pretreated sections, and intracellular aggregates of Aβ 42 were observed in the cytoplasm of hippocampal pyramidal cells. HP-tau: -, negative; +, AT8-positive cells limited to the entorhinal cortex; ++, AT8-positive cells in the entorhinal cortex and throughout the hippocampus. F, female; M; male, ND, no data; a, weak AT8 positivity on the surface of cerebral cortex