Table 1.
Preliminary | Time 1 | Time 2 | Time 3 | |
---|---|---|---|---|
PCL-C | X | |||
PHQ-9 | X | |||
ISI | X | X | X | X |
Demographics | X | |||
Medical history | X | |||
MMSE | X | |||
SDS-CL | X | |||
MINI | X | X* | X* | |
CAPS | X | X | X | |
HRSD-17 | X | X | X | |
PSG | X | X | X | |
Serum | * X** | * X** | * X** | |
Saliva | ** X*** | ** X*** | ** X*** |
PCL-C: PTSD Checklist – Civilian Version; PHQ-9: Physician Health Questionnaire – 9; ISI: Insomnia Severity Index; Medical history includes medication usage and sleep symptoms; SDS-CL: Sleep Disorders Symptoms Checklist; MMSE: Mini Mental Status Exam; MINI: MINI International Neuropsychiatric Exam; CAPS: Clinician-Administered PTSD Scale; HRSD-17: Hamilton Rating Scale for Depression – 17; PSG: Polysomnography.
At Time 2 and Time 3 only the Depression module of the MINI is administered.
One blood draw is conducted within two hours prior to going to bed; another within one hour of rising.
Two evening samples are collected at 7:00 PM and 9:00 PM. Five morning samples are collected at waking, then waking + 15 minutes, +30 minutes, +60 minutes and +90 minutes.