Table 3.
Biomarkers of iodine status
| Iodine | Placebo | Effect (95 % CI) | P value | |
|---|---|---|---|---|
| Cord blood | n = 19 | n = 22 | ||
| Free triiodothyronine, pmol/la | 2.3 (0.4) | 2.3 (0.6) | 0.0 (−0.4, 0.3) | 0.81 |
| Free thyroxine, pmol/la | 14.4 (2.1) | 13.8 (2.3) | 0.6 (−0.9, 2.2) | 0.40 |
| Thyroid-stimulating hormone, mIU/lb | 8.2 (5.9–13.5) | 6.6 (4.5–9.6) | N/A | 0.25 |
| Thyroglobulin, μg/lb | 73.0 (48.0–100.0) | 64.0 (44.0–121.0) | N/A | 0.66 |
| (n = 28) | (n = 29) | |||
| Newborn TSH, mIU/la | 2.1 (1.0) | 2.2 (1.2) | −0.1 (−0.7, 0.5) | 0.79 |
| Newborn TSH > 5c | 0 (0.0) | 0 (0.0) | N/A | N/A |
| (n = 20) | (n = 25) | |||
| Breast milk iodine at 6 weeks’ post-partum, μg/lb | 106.0 (84.0–146.0) | 124.0 (76.0–155.0) | N/A | 0.74 |
CI confidence interval, N/A not applicable, TSH thyroid-stimulating hormone
aData are presented as mean (standard deviation), and the treatment effect is the difference in means
bData are presented as median (interquartile range)
cData are presented as number (percentage)