Table.

Hemostatic Parameters in Case 1 and Case 2

	Case 1				Case 2
	Pre-surgery	Post-surgery			Pre-surgery	Post-surgery
		2 weeks	2 months	2 years		3 weeks	5 months
Hemoglobin g/L	130	105	128	124	140	110	133
Platelets × 109/L	253	528	246	226	133	295	195
aPTT (s)	36	34	38	34	28	25	26
FVIII:C IU/mL#	0.55	0.90	0.73	1.20	1.46	2.03	1.91
VWF:Ag IU/mL##	0.64	0.71	0.64	0.85	0.80	0.83	nd
VWF:RCo IU/mL###	0.35	0.43	0.47	0.89	0.62	0.68	0.73
VWF:RCo/VWF:Ag	55%	60%	73%	104%	77%	82%	-
Multimers	Normal	-	-	-	Normal	-	-
Platelet aggregation	Normal	-	-	-	Normal	-	Normal
PFA: Col/Epi*(s)	274–282	130	152	106	300->300	158	128
PFA: Col/ADP**(s)	230–251	122	107	123	153–224	nd	79
Blood type	O+				B+

^#Institutional normal range: 0.56–1.72 IU/mL

^##Institutional normal range for patients > 3 months of age: 0.47–1.39 IU/mL for blood group 0, 0.84–1.92 IU/mL for non blood group 0

^###Institutional normal range for patients > 3 months of age: 0.38–1.22 IU/mL for blood group 0, 0.73–1.81 IU/mL for non blood group 0)

^*Collagen/epinephrine cartridge: normal <168 seconds

^**Collagen/ADP cartridge: normal <123 seconds

aPTT, activated partial thromboplastin time; nd, not done