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. 2015 Oct 1;13(5):311–319. doi: 10.1089/bio.2015.0032

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© The Author(s) 2015; Published by Mary Ann Liebert, Inc.

This Open Access article is distributed under the terms of the Creative Commons Attribution Noncommercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited.

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FIG. 3. — GTEx Pathology Review. Certain tissues were not considered acceptable for GTEx analysis purposes. (a, b) Autolysis. (a) Well-preserved pancreas with distinguishable exocrine and endocrine elements (RNA integrity number [RIN] 6.3). (b) Severely autolyzed pancreas (RIN 2.4). (c, d) Heterogeneous tissue sampling. (c) Well-preserved gastric mucosa with a RIN of 7.3. The higher RIN reflects multiple cell types: the abundant well-fixed gastric glands in the mucosal layer combined with muscularis mucosa. (d) Poorly preserved colon mucosa with a RIN of 7.3. Although the mucosa was also the intended target in this biospecimen, it was badly autolyzed and the RIN reflects the residual colon muscularis propria. (e, f) Acceptable diseased tissues. (e) Normal thyroid. (f) Thyroid with Hashimoto's germinal center formation was identified but was still considered to be eligible for the GTEx study. Color images available online at www.liebertpub.com/bio