T3SS1 and T3SS2 effectors are produced and secreted at similar levels by POR and CAB strains. (a) Secretion of T3SS1 effectors, VopQ and VopS, from T3SS1-induced strains grown in DMEM for 3 h at 37 °C. (b) Secretion of T3SS2 effectors, VopA and VopL, from T3SS2-induced strains grown in MLB with 0.05% bile salts for 3 h at 37 °C. Proteins from bacterial lysates or TCA-precipitated media detected by immunoblot analysis using anti-VopQ, anti-VopS, anti-VopA, and anti-VopL antibodies. Asterisk represents nonspecific band recognized by antibody and LC is abbreviation for loading control.