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. Author manuscript; available in PMC: 2016 Sep 1.
Published in final edited form as: Pigment Cell Melanoma Res. 2015 Sep;28(5):590–598. doi: 10.1111/pcmr.12392

Figure 4.

Figure 4

Signaling pathways modulated by RAC1 mutants. (A) Significance analysis of microarray for RPPA of parental melan-a cells and melan-a cells expressing RAC1 WT, RAC1 P29S, and RAC1 Q61L. Expression was normalized to the mean. (B) Venn diagram depicting number of proteins significantly regulated in, between, and among melan-a cells expressing RAC1 WT, RAC1 P29S, and RAC1 Q61L. (C) Top ten KEGG pathways enriched in the 42 proteins similarly regulated by RAC1 WT, RAC1 P29S, and RAC1 Q61L.