Table 3. Factors related to various ocular motor abnormalities in patients with SCA types 1, 2, 3, and 6.
Ocular Motor Symptom/Abnormality | Disease | Factors Reaching Significance |
---|---|---|
Diplopia | SCA 3 | Longer disease duration, higher SARA score, and poorer functional stage |
Abnormal pursuit | SCA 1 | Lower SARA score |
SCA 2 | Lower SARA score | |
SCA 3 | Higher age and higher age at onset | |
SCA 6 | Shorter disease duration | |
Hypermetric saccades | SCA 1 | Higher age and higher age at onset |
SCA 2 | Lower SARA score and better functional stage | |
Hypometric saccades | SCA 2 | Poorer functional stage |
Horizontal ophthalmoparesis | SCA 3 | Higher SARA score |
Vertical ophthalmoparesis | SCA 1 | Higher SARA score and poorer functional stage |
SCA 3 | Higher repeats, higher SARA score, and poorer functional stage | |
Slow saccades | SCA 1 | Higher repeats, disease duration, higher SARA score, and poorer functional stage |
SCA 2 | Higher SARA score and poorer functional stage | |
SCA 3 | Higher repeats, disease duration, higher SARA score, and poorer functional stage |
SARA, Scale for Assessment and Rating of Ataxia; SCA, spinocerebellar ataxia.