Fig 8. Overexpression or silencing of adiponectin expression on the matrix metalloproteinase (MMP) activity of A549 cells.
Gelatin zymography was used to analyzed the activities of MMP-2/MMP-9, MMP-1/MMP-3, and MMP-13/MMP-14. (A–F) The activities of MMP-9, -1, and -14 were increased after the overexpression of adiponectin and decreased with the silencing of adiponectin. Expression of MMP-3 and -13 did not change regardless of adiponectin augmentation or silencing.