Fig 2. Associations of PIK3CG SNPs rs4288294 (A) and rs116697954 (B) with HDL2- and HDL3-cholesterol concentrations.

The HDL-cholesterol subfractions HDL2 and HDL3 were obtained by ultracentrifugation. Adjustment of HDL2- and HDL3-cholesterol concentrations (N = 34) was achieved by multiple linear regression modelling with gender, age, and BMI as confounding variables. The SNPs were tested in the dominant inheritance model. HDL–high-density lipoprotein; SNP–single nucleotide polymorphism.