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. 2015 Dec 10;10(12):e0143391. doi: 10.1371/journal.pone.0143391

Fig 4. Activation of MAPK is essential for DENV-induced B cell activation.

Fig 4

Mock or DENV-treated cells were cultured in the presence or absence of ERK (PD98059), p38 (SB203580) and JNK (SP600125) inhibitors. A) After 12 days culture, supernatants were harvested and IgM levels were measured by ELISA. B) After 48h, culture supernatants were harvested and IL-6 levels were measured by ELISA. Data are representative of at least four independent experiments. Statistical analysis were performed and p values are indicated in the figures.