. Author manuscript; available in PMC: 2015 Dec 10.

Published in final edited form as: Expert Rev Mol Diagn. 2015 May 2;15(6):725–733. doi: 10.1586/14737159.2015.1041378

Table 1.

Comparison of exosomal sensing platforms.

Method	Sensing principle	Target	Sensitivity	Throughput	Reference
nPLEX	SPR	Protein	~10³ exosomes	High (>100 arrays)	18
μNMR	Magnetic resonance	Protein	~10⁴ exosomes	Low (single channel)	17
ExoChip	Fluorescence	CD63+/Rab5+ EVs	0.5 pM	Low (three channels)	27
SOMAscan	Fluorescence	Protein	100 fM	Very high (1,129)	28
Microfluidic chip	Fluorescence	Protein	0.3 pg/mL	Low (single channel)	26
SPRi	SPR	Protein	5×10⁷ exosomes/cm²		29
BEAMing & digital PCR	Fluorescence	RNA	0.01% (mutant detection)	High	25
miRNA microarray/NanoString	Fluorescence	miRNA		Very high (> 1,000)	30