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. Author manuscript; available in PMC: 2016 Aug 12.
Published in final edited form as: Neuroendocrinology. 2015 Aug 12;102(4):256–266. doi: 10.1159/000438790

Figure 4.

Figure 4

LH is not always reliable biomarker of high frequency GnRH release. A. GnRH and LH release in a thyroidectomized ewe. Open circles mark pulses detected by the Cluster algorithm [46]. Adapted from [43]. B. GnRH and LH in a long-term castrate ram. Open arrowhead is time of portal vessel lesion for sampling; closed arrowheads mark detected pulses. Adapted from [44]. C. GnRH and LH release before, during and after treatment with naloxone (arrows, long arrow 100 mg, short arrows 50 mg dose). Angled arrowheads mark detected pulses. Adapted from [45].