Table 3.
Total lens protein and soluble protein levels of controls and HIE-treated cataractous Sprague–Dawley rats
Treatment | Lens proteins | ||
---|---|---|---|
Total protein (µg mL−1) | CRYAA (pg mL−1) | CRYAB (pg mL−1) | |
10 mL kg−1 NS | 2135 ± 158.0 | 167.3 ± 13.14 | 84.30 ± 3.303 |
NORM | 4369 ± 108.1*** | 673.2 ± 43.09*** | 153.7 ± 3.303*** |
30 mg kg−1 HIE | 3500 ± 39.67*** | 515.5 ± 34.77*** | 153.7 ± 3.303*** |
100 mg kg−1 HIE | 2915 ± 167.0** | 331.6 ± 22.76** | 117.3 ± 8.739** |
300 mg kg1 HIE | 3545 ± 83.48*** | 719.2 ± 6.571*** | 160.3 ± 5.721*** |
Values are mean ± SEM (n = 8). **P ≤ 0.01; ***P ≤ 0.001; ANOVA followed by Dunnett’s post hoc test
CRYAA alpha crystallin A, CRYAB alpha crystallin B, NS normal saline, NORM normal control