Table 4.

Pharmacokinetic parameters of triptolide by i.g. administration and transdermal delivery under microneedles.

Parameter	Unit	Administration method
i.g.	Transdermal
t1/2 (K)	h	0.595±0.321	10.831±3.414
t1/2 (Ka)	h	0.497±0.115	2.410±0.896
t1/2β	h	2.584±0.766	20.853±5.729
Tmax	h	0.982±0.282	6.592±1.591
Cmax	ng/mL	182.46±47.691	153.32±26.463
AUC0→∞	ng.h/mL	773.63±68.34	4038.45±527.74

Data are expressed as mean±SD, n=5.