Table 1. Demographic and clinical characteristics of the infants.
| Variable | BPD (n=24) | No BPD (n=38) | P value |
|---|---|---|---|
| Sex | |||
| Male:female | 20:4 | 29:9 | 0.896 |
| Birth weight (g)* | 1,125.0±117.8 | 1,181.8±121.4 | 0.923 |
| Gestational age (wk)* | 28+2 (26+3-31+6) | 29+1 (26+2-31+6) | 0.875 |
| Proteinuric preeclampsia | 16 (66.7) | 10 (27.3) | 0.036 |
| PROM | 8 (33.3) | 24 (63.2) | 0.151 |
| Chorioamnionitis | 4 (16.7) | 10 (26.3) | 0.681 |
| Apgar score* | |||
| At 1 minute | 2.5 (2-4) | 5 (1-6) | 0.242 |
| At 5 minutes | 7 (95-7) | 7 (4-7) | 0.875 |
| Multiplet | 8 (33.3) | 10 (26.3) | 0.714 |
| Antenatal steroid | 20 (83.3) | 24 (63.2) | 0.432 |
| Respiratory distress syndrome | 24 (100) | 38 (100) | - |
| No. of surfactant treatment (time)* | 1.7±0.5 | 1.6±0.5 | 0.499 |
| Patent ductus arteriosus | 4 (16.7) | 0 (0) | 0.118 |
| Mechanical ventilation (day)* | 21±13 | 10±11 | 0.006 |
| O2 administration (day)* | 33±3 | 17±18 | 0.002 |
| IVH≥grade 3 | 8 (33.3) | 0 (0) | 0.011 |
| Pulmonary hemorrhage | 0 (0) | 0 (0) | - |
| NEC≥stage II | 0 (0) | 4 (10.5) | 0.529 |
| Culture-proven sepsis | 0 (0) | 0 (0) | - |
| Classification of BPD | - | ||
| No BPD | 0 (0) | 38 (100) | |
| Mild | 16 (66.7) | 0 (0) | |
| Moderate | 6 (25.0) | 0 (0) | |
| Severe | 2 (8.3) | 0 (0) |
Values are presented as mean±standard deviation, median (interquartile range) or number (%). The frequencies were compared by using the chi-square test.
PROM, premature rupture of membranes; BPD, bronchopulmonary dysplasia; IVH, intraventricular hemorrhage; NEC, necrotizing enterocolitis.
*Mann-Whitney U test.