Table 1.
Demographic and Clinical Variables by Study Site
| Variables | Site 1 (N = 14) | Site 2 (N = 60) | t/χ 2 | P |
|---|---|---|---|---|
| Age | 56.4 (9.9) | 47.3 (12.9) | 2.49 | .02 |
| Sex (female %) | 42.9% | 73.3% | 4.81 | .03 |
| Bipolar (%) | 21.4% | 26.7% | 0.16 | .69 |
| Current episode duration (wk) | 43.4 (51.3) | 26.7 (33.4) | 1.50 | .14 |
| Previous ECT (%) | 57.1% | 41.7% | 1.10 | .29 |
| Benzodiazepines (% yes) | 42.9% | 46.7% | 0.07 | .80 |
| Antidepressant during ECT (% yes) | 85.7% | 95.0% | 1.55 | .21 |
| Premorbid IQ | 102 (16.7) | 110 (10.4) | -1.70 | .11 |
| ECT placement | 1.17 | .28 | ||
| RUL (%) | 85.7% | 71.7% | ||
| Bitemporal (%) | 14.3% | 28.3% | ||
| Pulse width (% ≤ .7ms) | 50.0% | 48.3% | 0.01 | .91 |
| Anaesthetic (%) | 2.60 | .11 | ||
| Propofol | 14.3% | 36.7% | ||
| Thiopentone | 85.7% | 63.3% | ||
| Number of ECT | 8.79 (2.67) | 8.87 (3.18) | -0.09 | .93 |
| MMSE at baseline | 27.1 (3.32) | 28.6 (1.57) | -1.71 | .11 |
| Time to reorientation post ECT 3 (min) | 25.4 (19.3) | 20.7 (12.9) | 0.88 | .39 |
| Time to reorientation post ECT 6 (min) | 31.0 (18.6) | 21.7 (16.0) | 1.90 | .06 |
| AMI-SF consistency post ECT (%) | 70.3 (16.9) | 74.7 (15.5) | -0.93 | .36 |
| Verbal fluency consistency post ECT (%) | 74.5 (19.8) | 76.5 (23.3) | -0.30 | .77 |
| MADRS baseline | 33.4 (8.42) | 35.5 (5.81) | -0.92 | .37 |
| MADRS post ECT | 14.6 (12.9) | 20.8 (10.5) | -1.90 | .06 |
| Remission (% yes) | 57.1% | 13.3% | 12.9 | <.01 |
Remission was defined as MADRS score <10.
Abbreviations: AMI-SF, Columbia Autobiographical Memory Interview – Short Form; MADRS, Montgomery-Äsberg Depression Rating Scale; MMSE, Mini Mental State Examination; RUL, right unilateral.