Skip to main content
. Author manuscript; available in PMC: 2015 Dec 11.
Published in final edited form as: Circulation. 2014 Mar 28;130(23):e199–e267. doi: 10.1161/CIR.0000000000000041

Table 5. Selected Risk Factors and Biomarkers for AF.

Clinical Risk Factors References
 Increasing age (139)
 Hypertension (139)
 Diabetes mellitus (139)
 MI (139)
 VHD (139)
 HF (38, 139)
 Obesity (140-142)
 Obstructive sleep apnea (142)
 Cardiothoracic surgery (137)
 Smoking (143)
 Exercise (144-146)
 Alcohol use (147-149)
 Hyperthyroidism (150-152)
 Increased pulse pressure (153)
 European ancestry (154)
 Family history (155)
 Genetic variants (156-159)
Electrocardiographic
 LVH (35)
Echocardiographic
 LA enlargement (35, 160)
 Decreased LV fractional shortening (35)
 Increased LV wall thickness (35)
Biomarkers
 Increased CRP (86, 161)
 Increased BNP (162, 163)

AF indicates atrial fibrillation; BNP, B-type natriuretic peptide; CRP, C-reactive protein; HF, heart failure; LA, left atrial; LV, left ventricular; LVH, left ventricular hypertrophy; MI, myocardial infarction; and VHD, valvular heart disease.