Skip to main content
. Author manuscript; available in PMC: 2016 May 18.
Published in final edited form as: Kidney Int. 2015 Sep 30;88(6):1261–1273. doi: 10.1038/ki.2015.286

Fig. 3. Genes sensitive to genetic inhibition or pharmacological induction of Nrf2 in the mouse kidney.

Fig. 3

qPCR validation of genes that were shown to be (A) significantly downregulated in the kidneys of Nrf2−/− mice, or (B) significantly upregulated in the kidneys of Nrf2+/+ mice treated with CDDO-Me. Gene expression levels are normalized to those of Ppia. Data represent mean + S.D. of n=5 animals per group. Statistical analysis of qPCR data was performed with an unpaired t test or Mann-Whitney test *, P≤0.05; **, P≤0.01; ***, P≤0.001; N.S., non-significant.