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. Author manuscript; available in PMC: 2016 May 18.
Published in final edited form as: Kidney Int. 2015 Sep 30;88(6):1261–1273. doi: 10.1038/ki.2015.286

Fig. 5. Definition of the Nrf2-regulated renal proteome.

Fig. 5

iTRAQ analysis was performed on kidney tissue from Nrf2+/+ or Nrf2−/− mice treated with vehicle (DMSO) or CDDO-Me for 24 h. (A) Overview of iTRAQ findings. DE; differentially expressed. The relevant supplementary tables are indicated in the boxes. (B-C) Volcano plots depicting differentially expressed proteins in the kidneys of (B) Nrf2−/− mice, compared with Nrf2+/+ counterparts, and (C) Nrf2+/+ mice treated with CDDO-Me, compared to vehicle. Each point represents a single protein, with those shaded red found to be significantly different (raw P-value) between groups.