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. Author manuscript; available in PMC: 2016 May 18.
Published in final edited form as: Kidney Int. 2015 Sep 30;88(6):1261–1273. doi: 10.1038/ki.2015.286

Fig. 8. Nrf2 regulates the provision of NADPH and glutathione in the kidney.

Fig. 8

The (A) NADPH and (B) glutathione contents of kidney tissue from Nrf2+/+ or Nrf2−/− mice treated with vehicle (DMSO) or CDDO-Me for 24 h. (A) NADPH content is normalized to protein content and expressed as a percentage of vehicle-treated Nrf2+/+ mice. (B) Glutathione content is normalized to tissue weight and expressed as a percentage of vehicle-treated Nrf2+/+ mice. All data represent mean + S.D. of n=6 animals per group. Statistical analysis was performed using an unpaired t test; **, P≤0.01; ***, P≤0.001; N.S., non-significant.