Table 1.
O2 (N = 812) | No O2 (N = 514) | P- | |
---|---|---|---|
Age (years) | 68.3 ± 10.5 | 66.6 ± 11.0 | 0.004 |
Female (%) | 327 (40.3) | 211 (41.1) | 0.78 |
Smoking* | 4 (0.6 %) | 3 (0.6 %) | 0.003 |
Present | 471 (65.9 %) | 277 (57.4 %) | |
Past | 240 (33.6 %) | 203 (42.0 %) | |
Never | |||
BMI | 30.3 ± 6.9 | 28.5 ± 5.5 | <0.0001 |
IPF diagnosis (%) | 303 (37.3) | 170 (33.1) | 0.12 |
FVC% within 30 days** | 61.3 ± 18.9 | 77.5 ± 17.4 | <0.0001 |
DLCO% within 30 days*** | 37.5 ± 12.8 | 56.1 ± 16.5 | <0.0001 |
6MWD (feet) | 1070.6 ± 361.4 | 1421.4 ± 343.7 | <0.0001 |
Borg Dyspnea | 3.9 ± 2.0 | 2.9 ± 1.7 | <0.0001 |
Borg Exertion**** | 3.2 ± 2.1 | 2.4 ± 1.8 | <0.0001 |
HR baseline | 79.7 ± 13.9 | 78.1 ± 13.2 | 0.03 |
HR at 6 min | 109.7 ± 15.9 | 110.9 ± 15.8 | 0.18 |
HR rise | 30.0 ± 14.5 | 32.8 ± 13.7 | 0.0004 |
SpO2 baseline | 97.4 ± 1.9 | 95.2 ± 1.7 | <0.0001 |
SpO2 at 6 min | 88.1 ± 5.3 | 88.7 ± 5.4 | 0.04 |
SpO2 drop | 9.2 ± 5.5 | 6.4 ± 5.2 | <0.0001 |
Values are mean and standard deviation or count (percent); IPF idiopathic pulmonary fibrosis; BMI body mass index; FVC% percent predicted forced vital capacity; DLCO% percent predicted diffusing capacity of the lung for carbon monoxide; 6MWD distance walked during six-minute walk test (6MWT); SpO2 peripheral oxygen saturation; HR heart rate; O2 completed 6MWT using supplemental oxygen; No O2 completed 6MWT without using supplemental oxygen; *N = 715 for O2 users and 483 for non-users; **N = 446 for O2 users and 251 for non-users; ***N = 211 for O2 users and 123 for non-users; ****N = 672 for O2 users and 415 for non-users