Table 2.
Body and brain weight of NEX-Tsc2 mice at P0 and P10
| Genotype | P0 | P10 | ||
|---|---|---|---|---|
| Body weight (g) | Brain weight (g) | Body weight (g) | Brain weight (g) | |
| WT | 1.48 ± 0.03 (n = 23) |
0.12 ± 0.00 (n = 23) |
5.74 ± 0.11 (n = 23) |
0.36 ± 0.00 (n = 22) |
| HT | 1.38 ± 0.07 (n = 4) |
0.12 ± 0.01 (n = 4) |
6.14 ± 0.2 (n = 13) |
0.36 ± 0.01 (n = 10) |
| KO | 1.36 ± 0.06 (n = 5) |
0.12 ± 0.01 (n = 5) |
4.00 ± 0.36* (n = 7) |
0.36 ± 0.01 (n = 5) |
| WT + RAD001 | ND | ND | 3.03 ± 0.34 (n = 4) |
0.19 ± 0.01 (n = 4) |
| HT + RAD001 | ND | ND | 3.27 ± 0.09 (n = 10) |
0.21 ± 0.00 (n = 10) |
| KO + RAD001 | ND | ND | 2.80 ± 0.26 (n = 3) |
0.21 ± 0.00 (n = 3) |
Values indicate the average weight ± SEM. ND, Not determined.
*Statistically significant difference between KO and WT mice in the untreated group (Kruskal–Wallis test, p < 0.001p).