Table 1.
Demographic and clinical characteristics of subjects implanted with bilateral mesial temporal electrodes (N = 82)
| Female | 47.6% (39/82) |
|---|---|
| Age in yearsa (mean, SD, range) | 37.2 ± 10.9 (18–60) |
| Duration of epilepsy in yearsa (mean, SD, range) | 19.9 ± 13.2 (2–57) |
| Number of AEDs at enrollmenta (mean, SD, range) | 2.7 ± 1.1 (1–5) |
| Preimplantb seizure frequency per month (mean, SD, range) | 13.7 ± 17.4 (3.0–88.3) median = 7.0 |
| Prior intracranial monitoring | 42.7% (35/82) |
| Prior epilepsy surgery | 7.3% (6/82) |
| Prior VNS | 26.8% (22/82) |
| Hippocampal atrophy or mesial temporal sclerosis | 63.4% (52/82) |
| Unilateral | 34.6% (18/52) |
| Bilateral | 65.4% (34/52) |
| Preimplant electrographic seizuresb | |
| Bilateral | 86.6% (71/82) |
| Unilateral | 13.4% (11/82) |
| Left | 63.6% (7/11) |
| Right | 36.4% (4/11) |
a
At time of enrollment into the pivotal study.
b
Preimplant refers to evaluation prior to implantation of the RNS Neurostimulator and NeuroPace leads.