Table 3.

Diagnostic performance of selected rest and stress-echocardiography variables

	Sensitivity (95% CI)	Specificity (95% CI)	Youden index
Wall-motion reversible abnormalities	66% (52.46–80.05)	93.94% (79.77–99.26)	0.599
WM reversible abnormalities or CFR–LAD <2	89.8% (77.77–96.6)	69.7% (51.29–84.41)	0.595
Rest global longitudinal strain <−20.72%	81.63% (67.97–91.24)	84.85% (68.1–94.89)	0.665
Average early systolic lengthening >12.66 ms	59.18% (44.21–73)	63.64% (45.12–79.59)	0.228

Table shows sensitivity, specificity, and Youden index to diagnose at least one coronary artery stenosis ≥50% for stress-echo parameters (wall-motion abnormalities, wall motion combined with CFR–LAD <2) and for rest strain parameters (GLS and ESL) considered as categorical variables. In this case <2 was used as cutoff for CFR–LAD, as indicated by previous literature, while the best cutoff found in current study (−20.72%) was used for GLS and ESL (>12.66 ms).