Figure 2.

Human C1-inhibitor (C1INH) suppresses Plasmodium falciparum merozoite invasion of red blood cells (RBCs). A and B, RBC invasion inhibition after 1 (A) and 2 (B) cycles of in vitro culture of 2 different P. falciparum strains (FUP and 3D7) in the presence of different concentrations of human C1INH. Results are expressed as the percentage inhibition relative to ovalbumin controls. The figures show 1 representative experiment from 3 that were performed. Error bars show standard errors of the mean. *P < .05 and **P < .0001, versus control.