Table 1. Baseline characteristics.
| Total population | Propensity-matched population | |||||
|---|---|---|---|---|---|---|
| No Statin(n = 299) | Statin(n = 756) | p value | No Statin(n = 256) | Statin(n = 256) | p value | |
| Age | 66.6 ± 11.7 | 66.8 ± 12.4 | 0.83 | 66.7 ± 11.5 | 66.2 ± 12.0 | 0.64 |
| Gender (male) | 218 (73%) | 517 (68%) | 0.15 | 72 (28%) | 72 (28%) | 0.99 |
| Body mass index (kg/m2) | 23.3 ± 3.5 | 23.5 ± 3.2 | 0.35 | 23.1 ± 3.5 | 22.9 ± 2.8 | 0.54 |
| Systolic blood pressure (mmHg) | 122.6 ± 31.6 | 127.8 ± 26.9 | < 0.01 | 124.0 ± 28.7 | 127.8 ± 27.1 | 0.13 |
| Diastolic blood pressure (mmHg) | 76.2 ± 19.9 | 78.6 ± 16.6 | 0.04 | 77.1 ± 18.2 | 78.1 ± 15.7 | 0.53 |
| Heart rate (bpm) | 84.1 ± 23.3 | 86.5 ± 21.4 | 0.11 | 84.4 ± 22.5 | 85.9 ± 21.4 | 0.45 |
| Final diagnosis (STEMI) | 172 (57%) | 452 (60%) | 0.50 | 103 (40%) | 110 (43%) | 0.59 |
| Killip class (more than II) | 140 (49%) | 316 (44%) | 0.15 | 124 (50%) | 109 (44%) | 0.18 |
| Previous statin use | 14 (5%) | 62 (25%) | 0.03 | 11 (4%) | 9 (3%) | 0.82 |
| Cardiovascular risk factors | ||||||
| Hypertension | 158 (53%) | 410 (55%) | 0.61 | 136 (53%) | 133 (52%) | 0.86 |
| Diabetes mellitus | 110 (37%) | 255 (34%) | 0.36 | 94 (37%) | 97 (38%) | 0.85 |
| Hyperlipidemia | 14 (5%) | 112 (15%) | < 0.01 | 10 (4%) | 12 (5%) | 0.83 |
| Current smoking | 122 (42%) | 284 (38%) | 0.29 | 108 (42%) | 108 (42%) | 0.99 |
| Previous coronary artery disease | 46 (15%) | 144 (19%) | 0.16 | 38 (15%) | 34 (13%) | 0.70 |
| Laboratory findings | ||||||
| Ejection fraction | 33.9 ± 6.2 | 33.8 ± 5.9 | 0.72 | 34.3 ± 6.0 | 34.3 ± 5.8 | 0.89 |
| Glucose (mg/dL) | 194.9 ± 103.4 | 187.7 ± 93.9 | 0.27 | 201.1 ± 110.4 | 197.1 ± 105.5 | 0.68 |
| Creatinine (mg/dL) | 1.4 ± 1.7 | 1.2 ± 1.1 | 0.02 | 1.2 ± 1.2 | 1.3 ± 1.6 | 0.38 |
| Max-CK-MB (mg/dL) | 154.6 ± 213.6 | 144.3 ± 184.7 | 0.44 | 146.8 ± 189.4 | 157.4 ± 213.1 | 0.55 |
| Max-cTnI (mg/dl) | 79.5 ± 250.4 | 72.2 ± 190.1 | 0.64 | 83.0 ± 181.2 | 77.8 ± 234.3 | 0.79 |
| Total cholesterol (mg/dL) | 169.1 ± 36.9 | 182.9 ± 48.4 | < 0.01 | 170.9 ± 45.6 | 168.8 ± 36.4 | 0.58 |
| Triglyceride (mg/dL) | 105.6 ± 63.3 | 120.3 ± 86.0 | < 0.01 | 109.1 ± 68.9 | 103.5 ± 62.5 | 0.34 |
| HDL-cholesterol (mg/dL) | 45.5 ± 26.7 | 44.1 ± 12.9 | 0.28 | 44.0 ± 14.0 | 45.6 ± 27.8 | 0.43 |
| LDL-cholesterol (mg/dL) | 108.4 ± 58.1 | 117.9 ± 41.9 | < 0.01 | 105.4 ± 38.3 | 104.6 ± 33.8 | 0.80 |
| hsCRP (mg/dL) | 7.7 ± 25.1 | 8.1 ± 26.6 | 0.81 | 11.3 ± 36.8 | 8.3 ± 26.6 | 0.31 |
| NT-proBNP (ng/dL) | 5510.2 ± 8927.4 | 4915.7 ± 7700.0 | 0.35 | 5853.1 ± 9139.0 | 5693.0 ± 9213.9 | 0.86 |
| HbA1C (%) | 6.8 ± 1.7 | 6.6 ± 1.5 | 0.13 | 6.7 ± 1.4 | 6.8 ± 1.7 | 0.37 |
| Discharge medications | ||||||
| Aspirin | 289 (97%) | 753 (99%) | < 0.01 | 250 (98%) | 254 (99%) | 0.28 |
| Clopidogrel | 287 (96%) | 745 (98%) | 0.01 | 248 (97%) | 251 (98%) | 0.58 |
| Calcium-channel blocker | 14 (5%) | 42 (6%) | 0.57 | 13 (5%) | 18 (7%) | 0.46 |
| Beta-blocker | 237 (79%) | 627 (83%) | 0.16 | 208 (81%) | 208 (81%) | 0.99 |
| ACE inhibitor | 158 (53%) | 435 (57%) | 0.17 | 136 (53%) | 144 (56%) | 0.53 |
| Angiotensin-receptor blocker | 80 (27%) | 199 (26%) | 0.88 | 71 (28%) | 62 (24%) | 0.42 |
| Angiographic findings | ||||||
| Stenotic vessels | ||||||
| 1 vessel disease | 93 (32%) | 258 (35%) | 0.38 | 81 (32%) | 85 (33%) | 0.78 |
| 2 vessel disease | 88 (30%) | 234 (31%) | 0.67 | 75 (29%) | 80 (31%) | 0.70 |
| 3 vessel disease | 97 (33%) | 233 (30%) | 0.32 | 87 (34%) | 80 (21%) | 0.57 |
| Left main coronary artery involved | 15 (5%) | 30 (4%) | 0.44 | 13 (5%) | 11 (4%) | 0.83 |
| ACC/AHA lesion class | ||||||
| Type A or B1 | 98 (32%) | 113 (17%) | < 0.01 | 83 (32%) | 80 (31%) | 0.55 |
| Type B2 or C | 201 (67%) | 554 (83%) | < 0.01 | 173 (68%) | 176 (69%) | 0.55 |
| Pre TIMI flow 0/1 | 183 (66%) | 425 (60%) | 0.38 | 148 (58%) | 136 (56%) | 0.65 |
| Post TIMI flow 3 | 246 (93%) | 647 (94%) | 0.59 | 218 (93%) | 226 (95%) | 0.44 |
| Target stent length | 24.2 ± 6.1 | 24.4 ± 6.9 | 0.59 | 24.1 ± 6.6 | 24.1 ± 6.1 | 0.85 |
| Target stent diameter | 3.1 ± 0.4 | 3.1 ± 0.4 | 0.89 | 3.1 ± 0.4 | 3.1 ± 0.4 | 0.77 |
| Total stent number | 1.5 ± 0.9 | 1.6 ± 0.8 | 0.40 | 1.6 ± 0.8 | 1.5 ± 0.9 | 0.49 |
CK-MB, creatine kinase MB; cTnI, cardiac troponin I; cTnT, cardiac troponin T; GFR, glomerular filtration rate; HDL, high-density lipoprotein; hsCRP, high-sensitivity C-reaction protein; LDL, low-density lipoprotein; NT-pro BNP, N-terminal prohormone of brain natriuretic peptide; ACC/AHA, American College of Cardiology/American Heart Association; TIMI, Thrombolysis in Myocardial Infarction