Table 2.

Simple Tow-Tiered Confocal Laser Endomicroscopy Classification for Gastric Superficial Lesions [17]

Feature	Non-cancerous lesions	Cancer/HGIN lesions
Architecture	Orderly ranged glands with regular pit patterns, or mildly heterogeneous in arrangement and distribution	Irregularity in glandular size and shape; disorganised or destroyed pits and glands
Cells	Regular in shape and size; mildly increase in epithelial stratification; normal cell polarity	Irregular cells with disordered appearance; severe stratification; loss of cell polarity

HGIN, high grade intraepithelial neoplasia.