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. 2015 Dec 11;10(12):e0144606. doi: 10.1371/journal.pone.0144606

Fig 6. PIC stimulated apoptosis while Ex4 reduced PIC-induced apoptosis in insulin-producing cells from human iPS cells.

Fig 6

(a) Immunostaining of insulin-producing cells differentiated from human iPS cells. Insulin-positive cells were detected in purple, transfected cells in red with TI, and TUNEL-positive cells in green. Scale bars = 200 μm. (b) TUNEL staining of control cells with or without 100nM Ex4 and PIC-transfected cells with or without 100 nM Ex4. (c) TUNEL-positive cells in TI-positive insulin-producing cells. The error bars represent SE. The asterisk indicates significant difference (p<0.05). NS represents no significant difference.