Table 2. Immunodominant regions and the accuracy of epitope prediction servers.
Antigen | MHC | Dominant peptide sequence a | SYF. b | IEDB (I) c | IEDB (II) d |
---|---|---|---|---|---|
PfUIS3 | H-2 d | GLQENRNISLSKYQENKAVM | <20 | 13 | 11.23 |
H-2 b | SNDQKDSHVNNMEYMQKFVQ | 28 | 0.2 | >50 | |
HLA-A2 | SKYQENKAVMDLKYHLQKVY | 23 | 3 | N/A | |
PfLSA1 | H-2 d | SENERGYYIPHQSSLPQDNR | 27 | 0.3 | 40.49 |
PfLSAP2 | H-2 d | ELLIKEHDDYNSIYNYINNE | 23 | 0.7 | 73.06 |
H-2 b | LIQNILLSNVSLISGSHLYKRNSRKFAEGY | 25 | 0.4 | 27.70 | |
HLA-A2 | KKEKIKCGTFFGYIFLSKFM | <20 | 3.45 | N/A |
a Dominant peptide identified in the ELISpot mapping assay.
b Score given by SYFPEITHI prediction server.
c Percentile rank given by IEDB MHC Class I binding server.
d Percentile rank given by IEDB MHC Class II binding server.