Skip to main content
. 2015 Dec 11;10(12):e0144597. doi: 10.1371/journal.pone.0144597

Fig 14. Expression of GLP-1 receptor in the islets of beta-cell-specific Pax6 KO mice.

Fig 14

Double immunofluorescence staining of pancreatic cryosections from 4 month old mice at 6 weeks after tamoxifen induction. GLP-1 receptor is expressed in both YFP+ and YFP- insulin+ cells in the control islets (a-d). In beta-cell-specific Pax6 KO islets, GLP-1 receptor expression is lost from the YFP labeled Pax6-deficient cells (arrowheads e-h) but maintained in the YFP- insulin+ cells (arrows e-h).