Table 1. Demographic data.
| Control (Group 1) (n = 9) | Neonatal seizures but no epilepsy (Group 2) (n = 9) | Neonatal seizures with later epilepsy (Group 3) (n = 14) | |
|---|---|---|---|
| Sex: No.(%) | |||
| F | 3(33) | 2(22) | 11(79)* |
| M | 6(67) | 7(78) | 3(21) |
| Mean gestational age (week±SD) | 37.92±1.81 | 38.62±1.44 | 38.50±1.53 |
| Median seizure onset age(days after birth) | - | 6 | 4.5 |
| Underlying diseases: No.(%) | |||
| No | 9(100) | 2(22) | 2(14) |
| Perinatal hypoxemia or asphyxia | - | 2(22) | 2(14) |
| Intracranial hemorrhage | - | - | 1(7) |
| Central nervous system infection | - | 1(11) | 1(7) |
| Congenital diaphragmatic hernia | - | 1(11) | 1(7) |
| Congenital heart diseases | - | - | 2(14) |
| Suspected pachygyria | - | - | 1(7) |
| Chromosomal anomaly | - | 1(11) | 4(29) |
| Sepsis | - | 1(11) | - |
| Neonatal jaundice | - | 1(11) | - |
| Seizure type: No. (%) | |||
| Motor automatism | - | 4(44.4) | 3(21.4) |
| Tonic | - | - | 1(7.14) |
| Clonic | - | 2(22.2) | 2(14.3) |
| Myoclonic | - | - | 1(7.14) |
| Tonic + Clonic | - | 1(11.1) | 2(14.3) |
| Motor automatism + Clonic | - | 1(11.1) | 3(21.4) |
| Motor automatism + Tonic | - | 1(11.1) | 1(7.14) |
| Tonic + Clonic + Motor automatism | - | - | 1(7.14) |
| Mean EEG timing (PMA±SD) | 40.78±2.38 | 41.78±3.09 | 42.31±2.49 |
| EEG finding: No.(%) | |||
| Negative | 9(100) | 3(33) | 2(14) |
| Focal discharges | - | 5(56) | 6(43) |
| Multifocal discharges | - | - | 6(43)* |
| Cerebral dysfunction | - | 1(11) | - |
| Abnormal neuroimage: No.(%) | - | 3(33) | 11(79)* |
| Later developmental delay (%) | 1(11) | 1/7(14) | 9/11(82)* |
SD: standard deviation
*P<0.05 when compared with Group 1 or Group 2.