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. 2015 Dec 12;15:116. doi: 10.1186/s12935-015-0269-y

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© Yu et al. 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 8 — Effect of As₂O₃ (1 µM) + 5-FU (400 µM) on the expression levels of apoptotic-related factors protein in HBx-HepG2 cells pretreated with hypoxia (1 % O₂). Western blot assay was used to examine the effect of As₂O₃ + 5-FU on the expression levels of DR4, DR5, BCL-2, caspase 3, caspase 8 and caspase 9 protein in HBx-HepG2 cells pretreated with hypoxia (1 % O₂), band densities were normalized to β-actin. All data were expressed as mean ± s.e.m., n = 4; significant differences between Ctrl + 5-FU group and ATO + 5-FU group were indicated as *P < 0.05 (unpaired t-test)