Table 2.

Immune-reactivity score for expression of mTOR, p-mTOR, MMP2, MMP7, MMP9 in the tumor center and at the invasive front of type gastric cancer

Targets	Intestinal type (n = 86)			Diffuse type (n = 42)			Overall (N = 128)
	Tumor center	Invasive front	p-value	Tumor center	Invasive front	p-value	Tumor center	Invasive front	p-value
MMP2	4.10 ± 5.042	7.65 ± 7.782	<0.001*	2.93 ± 3.925	5.40 ± 6.688	0.005*	3.72 ± 4.721	6.91 ± 7.490	<0.001*
MMP7	5.43 ± 8.345	4.48 ± 7.680	0.008*	5.10 ± 8.798	4.50 ± 7.613	(0.128)	5.32 ± 8.463	4.48 ± 7.628	0.002*
MMP9	4.57 ± 7.362	3.97 ± 7.058	(0.227)	5.62 ± 7.821	4.71 ± 6.656	(0.144)	4.91 ± 7.501	4.21 ± 6.912	(0.097)
mTOR	10.95 ± 7.543	9.79 ± 8.778	0.025*	8.67 ± 6.091	9.12 ± 6.463	(0.589)	10.20 ± 7.156	9.57 ± 8.072	(0.127)
p-mTOR	3.42 ± 4.185	2.69 ± 4.610	0.008*	2.13 ± 2.662	2.76 ± 4.667	(0.545)	3.00 ± 3.792	2.71 ± 4.610	0.013*

Comparison between tumor center and invasive front has been done by the Mann–Whitney U-test with significant differences (p < 0.05) marked by an asterisk. Values are given as mean and standard deviation