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. 2015 Dec 1;2015(12):CD010994. doi: 10.1002/14651858.CD010994.pub2

5. SOF outcome 1.12 Low birth weight.

Trial Measure of effect Statistical approach1 Intervention Control
Kenyon 2012 RR 0.92 (0.74, 1.14) P = 0.43 Not cluster trial ‐ calculated OR 127/605 141/613
Mori 2015 Adjusted OR 0.65 (0.26 to 1.59) trial statistician (H Noma) calculated unpublished OR adjusted for cluster effects and significant variables Straight into RevMan 8/251 12/247
Richter 2014   Adjusted 67/377 52/414
Villar 1992 OR 0.88 (95% CI 0.67 to 1.16) Straight into RevMan 115/1033 130/1040
Villar 2001   Adjusted 910/11534 852/11040

1ICC from Piaggio 2001 paper of 0.0004 for ANC trial with average cluster size 426.