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. 2015 Dec 1;2015(12):CD010994. doi: 10.1002/14651858.CD010994.pub2

11. SOF outcome 2.10 Low birthweight.

Trial Statistical approach1 Intervention Control
Klerman 2001 Straight into RevMan ‐ not cluster trial 39/311 33/296
Le roux 2013 Calculated adjusted OR 88/608 123/549

ICC from Piaggio paper of 0.0004 for ANC trial with average cluster size 426