Chavane 2014.

Trial name or title	Implementation of evidence‐based ANC in Mozambique. Location: antenatal clinics in3 regions of Mozambique. Trial Registration: Pan African Clinical Trial Registry database. Identification number: PACTR201306000550192.
Methods	Cluster‐randomised trial.
Participants	"Clinics were eligible if (1) they were not already implementing the proposed ANC model; (2) they served at least 200 new pregnant women per year; (3) they had midwives or nurses midwives among their personnel; and (4) they were willing to participate. All women attending ANC visits at the participating clinics will be eligible to receive the ANC package."
Interventions	Target: health system. "The aim of this study is to determine the effect of an intervention designed to increase the use of evidence‐based practices included in the ANC package by midwives (and other health professionals) in prenatal clinics in Mozambique. Specifically, we will assess the effect of the intervention on practices related to the detection, treatment and prevention of major health‐related conditions (e.g., anaemia, and infectious diseases such as HIV/AIDS, malaria, and congenital syphilis)." Arm 1: the intervention has 4 components: ANC kits for clinics, storage for ANC kits, tracking system, training for staff. Arm 2: standard care.
Outcomes	Primary outcome: administration of a set of practices during first ANC visit Secondary outcome: composite of several practices. • Frequency of women receiving screening for syphilis. • Frequency of women receiving screening for HIV. • Frequency of women receiving screening for anaemia. • Frequency of women receiving screening for hypertension. • Frequency of women receiving tetanus toxoid. • Frequency of women receiving intermittent preventive malaria treatment. • Frequency of women receiving iron supplementation. • Frequency of women receiving anti‐parasitic treatment (de‐worming). • Frequency of syphilis sero‐positive women receiving the administration of syphilis treatment. • Frequency of HIV sero‐positive women receiving administration of antiretroviral treatment.
Starting date	July 2013‐March 2015.
Contact information	Leonardo Chavane ‐ leochavane@gmail.com
Notes	Funding ‐ World Health Organization, Department of Reproductive Health and Research.