Table 4. Association Analysis for validated BMI increasing SNPs and Alzheimer’s Disease, Dementia Probability, and Memory Function.

			Late Onset Alzheimer’s Disease				Dementia		Memory
			GERAD		ADGC		HRS		HRS
Chr	SNP	A1	log(OR)	p	log(OR)	p	log(OR)	p	beta	p
Adipogenesis
1	rs1555543	C	−0.03	0.452	0.014	0.535
2	rs2890652	C	0	0.994	0.006	0.85	−0.038	0.421	−0.001	0.876
6	rs987237	G	0.03	0.542	−0.012	0.679	−0.051	0.268	0.002	0.553
11	rs4929949	C	0.02	0.63	0.013	0.565	0.01	0.784	−0.001	0.709
11	rs3817334	T	−0.03	0.486	−0.059	0.007	0.052	0.142	−0.005	0.141
12	rs7138803	A	0.09	0.999	−0.013	0.549	0.04	0.277	0.002	0.436
16	rs12444979	C	0.11	0.088	0.101	0.001	−0.001	0.981	−0.005	0.301
Appetite
1	rs2815752	A	−0.01	0.767	−0.003	0.902	−0.041	0.253	0.005	0.093
1	rs543874	G	0.01	0.883	−0.021	0.458	0.014	0.746	−0.003	0.373
2	rs2867125	C	0.05	0.39	−0.027	0.343	−0.018	0.701	0	0.93
3	rs9816226	T	0.04	0.449			0.04	0.391	−0.004	0.283
11	rs10767664	A	0	0.943			0.018	0.688	0.001	0.83
14	rs10150332	C	−0.03	0.55	0.019	0.476	−0.038	0.379	0.001	0.848
16	rs7359397	T	−0.06	0.18	−0.007	0.762	0.03	0.408	−0.007	0.026
16	rs1558902	A	−0.04	0.313			−0.004	0.905	0.002	0.568
18	rs571312	A	−0.04	0.47	−0.025	0.316	0.046	0.27	0	0.924
Cardiopulmonary Processes
1	rs1514175	A	0.03	0.426	−0.017	0.432	−0.019	0.588	−0.004	0.169
4	rs10938397	G	0.06	0.2	0.035	0.117	0.003	0.93	0.003	0.363
4	rs13107325	T	0.13	0.141	0.068	0.119	0.088	0.179	−0.001	0.86
14	rs11847697	T	−0.18	0.112	0.026	0.671
Unspecified Cellular Processes
2	rs713586	C	−0.1	0.018	0.006	0.784	−0.026	0.46	0.002	0.446
2	rs887912	T	0.08	0.074	−0.016	0.508	−0.011	0.778	−0.001	0.791
3	rs13078807	G	0.01	0.912	−0.031	0.236	−0.018	0.675	0	0.953
5	rs2112347	T	−0.03	0.656	−0.036	0.108	−0.006	0.863	0.001	0.675
5	rs4836133	A	0.14	0.002	0.012	0.613	0.025	0.482	−0.002	0.52
6	rs206936	G	−0.01	0.83	−0.024	0.365	−0.045	0.318	0.001	0.756
9	rs10968576	G	0.01	0.817	0.027	0.253	0.004	0.921	0.001	0.731
13	rs4771122	G	−0.04	0.403	−0.012	0.672
15	rs2241423	G	−0.05	0.295	−0.005	0.855	−0.037	0.367	0.007	0.043
19	rs29941	G	−0.02	0.731	−0.033	0.155	−0.017	0.65	0	0.907
19	rs2287019	C	−0.08	0.123	−0.002	0.949	−0.052	0.243	0.003	0.42
19	rs3810291	A	−0.06	0.19	−0.053	0.083	0.02	0.589	0.003	0.294
Other SNPs not included in Polygenic Score and not validated in Speliotes et al.
2	rs7566605	C	−0.073	0.111			−0.016	0.665	0	0.953
10	rs6602024	A	−0.001	0.993	−0.043	0.23	−0.073	0.208	0.006	0.218
10	rs10508503	C	0.046	0.693	−0.017	0.675
10	rs2116830	G	−0.058	0.291	0.02	0.503
16	rs1424233	A	−0.013	0.764	−0.022	0.312	0.003	0.936	0.001	0.669
18	rs1805081	G	0.009	0.832	0.017	0.436	0.001	0.969	−0.004	0.157
20	rs6013029	T	0.087	0.4	−0.031	0.533	−0.073	0.389	0.003	0.706