Table 1.
Distribution of clinical and demographic features of the patients, according to the different genotypes of MTHFR C677T
| Parameters | C677T N (%) | χ2 | p | ||
|---|---|---|---|---|---|
| CC | CT | TT | |||
| Gender | |||||
| Female | 35 (45.5) | 30 (39) | 12 (15.5) | 0.8 | 0.6 |
| Male | 12 (50) | 10 (41.7) | 2 (8.3) | ||
| Age (years) | |||||
| 40–60 | 27 (49.1) | 20 (36.4) | 8 (14.5) | 0.5 | 0.7 |
| 61–87 | 20 (43.5) | 20 (43.5) | 6 (13) | ||
| BMI (kg/m2) | |||||
| 18–24 | 14 (48.3) | 9 (31) | 6 (20.7) | 5.2 | 0.3 |
| 25–30 | 19 (43.2) | 22 (50) | 3 (6.8) | ||
| >30 | 14 (50) | 9 (32.1) | 5 (17.9) | ||
| Diabetes | |||||
| Yes | 14 (45.2) | 12 (38.7) | 5 (16.1) | 0.2 | 0.9 |
| No | 33 (47.1) | 28 (40) | 9 (12.9) | ||
| Dyslipidemia | |||||
| Yes | 15 (41.7) | 14 (38.9) | 7 (19.4) | 0.5 | 0.5 |
| No | 32 (49.2) | 26 (40) | 7 (10.8) | ||
| Stage of risk | |||||
| Low | 9 (34.6) | 12 (46.2) | 5 (19.2) | 6.35 | 0.2 |
| Medium | 24 (58.5) | 11 (26.8) | 6 (14.6) | ||
| High | 14 (41.2) | 17 (50) | 3 (8.8) | ||
| Smoking habit | |||||
| Yes | 6 (46.2) | 5 (38.5) | 2 (15.4) | 0.03 | 1 |
| No | 41 (46.6) | 35 (39.8) | 12 (13.6) | ||
FH family history, CC homozygous wild type, CT heterozygous, TT homozygous variant