Table 2.
Distribution of MTHFR genotype according to patient’s family history
| Family history | C677T N (%) | χ2 | p | ||
|---|---|---|---|---|---|
| CC | CT | TT | |||
| Hypertension | |||||
| Yes | 29 (50) | 23 (39.7) | 6 (10.3) | 1.6 | 0.5 |
| No | 18 (41.9) | 17 (39.7) | 8 (18.6) | ||
| Heart disease | |||||
| Yes | 8 (34.8) | 8 (34.8) | 7 (30.4) | 6.9 | 0.031 |
| No | 39 (50) | 32 (41) | 7 (9) | ||
| Stroke | |||||
| Yes | 7 (43.8) | 7 (43.8) | 2 (12.5) | 0.14 | 0.9 |
| No | 40 (47.1) | 33 (38.8) | 12 (14.1) | ||
| Diabetes | |||||
| Yes | 18 (40) | 20 (44.4) | 7 (15.6) | 1.4 | 0.5 |
| No | 29 (51.8) | 20 (35.7) | 7 (12.5) | ||
| Kidney disease | |||||
| Yes | 1 (12.5) | 6 (75) | 1 (12.5) | 4.9 | 0.08 |
| No | 46 (49.5) | 34 (36.6) | 13 (14) | ||
| Dyslipidemia | |||||
| Yes | 12 (48) | 8 (32) | 5 (20) | 1.4 | 0.5 |
| No | 35 (46.1) | 32 (42.1) | 9 (11.8) | ||
CC homozygous wild type, CT heterozygous, TT homozygous variant