Table 3.
Distribution of genotypes and alleles of MTHFR in patients and controls
| Patients N (%) | Control N (%) | OR (95 % CI) | p | |
|---|---|---|---|---|
| C677T | ||||
| CC | 47 (46.5) | 54 (52.9) | Ref. | |
| CT | 40 (39.6) | 45 (44.2) | 1 (0.6–1.8) | 1 |
| TT | 14 (13.9) | 3 (2.9) | 5.4 (1.4–19.8) | 0.008 |
| CC/CTa | 87 (86) | 99 (97) | Ref. | |
| TT | 14 (14) | 3 (3) | 5.3 (1.5–19.1) | 0.005 |
| CCb | 47 (46) | 54 (53) | Ref. | |
| CT/TT | 54 (54) | 48 (47) | 1.3 (0.7–2.2) | 0.4 |
| C | 134 (66) | 153 (75) | Ref. | |
| T | 68 (34) | 51 (25) | 1.5 (1–2.3) | 0.06 |
| HWE: p value | 0.27 | 0.11 | ||
HWE Hardy–Weinberg Equilibrium, N number
aRecessive model
bDominant model