5-HT1A
|
Hyperpolarization (GIRK channels) |
63% |
32% |
41% |
Anxiolytic (Levita et al, 2004; Gomes et al, 2011) |
Anxiolytic (Albert et al, 2014) |
5-HT7
|
Depolarization (Gs receptor) |
55% |
44% |
0% |
Unknown |
Depressive (Mnie-Filali et al, 2011) |
5-HT2C
|
Depolarization (Gq receptor) |
5% |
0% |
59% |
Anxiogenic (Heisler et al, 2007; Marcinkiewcz et al, 2015) |
Anxiogenic (Heisler et al, 2007; Kimura et al, 2009) |
5-HT1B
|
Presynaptic inhibition |
0% |
21% |
41% |
Unknown |
Aggression and impulsivity (Saudou et al, 1994; Nautiyal et al, 2015) |