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. 2015 Sep 2;41(1):45–57. doi: 10.1038/npp.2015.224

Table 1. The Symptomatology of PTSD and SEFL.

PTSD symptom SEFL parallel Source
Hyper-reactivity to mild stress, lasting at least 90 days Increased freezing to 1 shock or loud noise Rau et al, 2005
Propensity to form new fears (comorbidity with simple phobia Increased cued and contextual fear Rau et al, 2005
Anxiety Anxiety; open field; elevated plus maze Figure 1a and b
Co-morbid alcohol and drug abuse Increased voluntary alcohol consumption Meyer et al, 2013
Symptoms present >30 days post trauma >90 days Rau and Fanselow, 2009
Increased startle reactivity Hyper-reactivity to loud noise Figure 1c and d
Co-morbid depression Forced swim test Figure 1e and f

This table displays the overlap of symptoms of SEFL and PTSD, supporting the use of SEFL as a rodent model of PTSD.