Table 1.
The numeric density of the necrotic cells in the specimens obtained from the liver samples.
| Group | Numeric density of the necrotic hepatocytes (cm2) |
|---|---|
| Control | 4 ± 1.41a.b |
| LEP 20 µg/kg | 5.5 ± 1.87b.c |
| PARA 2 g/kg | 63 ± 16.26a.c |
| PARA 2 g/kg + LEP 10 µg/kg | 7.3 ± 1.21b.c |
| PARA 2 g/kg + LEP 20 µg/kg | 6.83 ± 2.48b.c |
Group 1: the control group; Group 2: 20 µg/kg leptin; Group 3: 2 g/kg paracetamol; Group 4: 2 g/kg paracetamol + 10 µg/kg leptin; Group 5: 2 g/kg paracetamol + 20 µg/kg leptin. LEP: the group receiving leptin, PARA: the group receiving paracetamol. a p < 0.05 comparison of the control group and paracetamol group, b p < 0.05 comparison of the control group and treatment group, and c p < 0.05 comparison of the paracetamol group and the treatment group. p < 0.05 was considered significant.