Table 2.
ALT and AST levels measured in the rat sera.
| Group | ALT (U/L) | AST (U/L) | TNF-α (pg/mL) |
|---|---|---|---|
| Control | 46.54 ± 11.67a | 88.58 ± 21.03a | 41.31 ± 2.36a |
| LEP 20 µg/kg | 55.25 ± 13.99a.b | 87.65 ± 11.08a | 48.31 ± 9.67a |
| PARA 2 g/kg | 196.14 ± 53.80d | 236.30 ± 37.18c | 154.88 ± 34.14b |
| PARA 2 g/kg + LEP 10 µg/kg | 80.75 ± 11.67b | 117.26 ± 25.31a | 43.25 ± 9.53a |
| PARA 2 g/kg + LEP 20 µg/kg | 122.83 ± 39.81c | 176.86 ± 57.44b | 50.75 ± 12.25a |
Group 1: the control group, Group 2: 20 µg/kg leptin. Group 3: 2 g/kg paracetamol. Group 4: 2 g/kg paracetamol + 10 µg/kg leptin. Group 5: 2 g/kg paracetamol + 20 µg/kg leptin. LEP: the group receiving leptin, PARA: the group receiving paracetamol. The results were analyzed using the post-hoc Duncan technique in the one-way ANOVA test. a p < 0.05 comparison of the control group and paracetamol group, b p < 0.05 comparison of the control group and treatment group, c p < 0.05 comparison of the paracetamol group and the treatment group (PARA 2 g/kg + LEP 10 µg/kg), d p < 0.05 comparison of the paracetamol group and the treatment group (PARA 2 g/kg + LEP 20 µg/kg), p < 0.05 was considered significant.