Table 3.
The GSH and MDA levels measured in the rat liver tissues.
| Group | GSH (nmol/mg protein) | MDA (nmol/mg protein) |
|
| ||
| Control | 3.84 ± 0.79c | 1.37 ± 0.23a |
| LEP 20 µg/kg | 3.33 ± 0.72b.c | 1.29 ± 0.76a |
| PARA 2 g/kg | 1.74 ± 0.55a | 4.04 ± 1.50b |
| PARA 2 g/kg + LEP 10 µg/kg | 3.35 ± 0.71b.c | 1.40 ± 0.78a |
| PARA 2 g/kg + LEP 20 µg/kg | 2.81 ± 0.66b | 1.91 ± 0.40a |
Group 1: the control group; Group 2: 20 µg/kg leptin; Group 3: 2 g/kg paracetamol; Group 4: 2 g/kg paracetamol + 10 µg/kg leptin; Group 5: 2 g/kg paracetamol + 20 µg/kg leptin. Malondialdehyde (MDA) levels and the Glutathione (GSH). LEP: the group receiving leptin, PARA: the group receiving paracetamol. The results were analyzed using the post hoc Duncan technique in the one-way ANOVA test. a p < 0.05 comparison of the control group and paracetamol group, b p < 0.05 comparison of the control group and treatment group, and c p < 0.05 comparison of the paracetamol group and the treatment group. p < 0.05 was considered significant.