Table 1.
Study | Case | Control | OR (95% CI) | P | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
AA | AG | GG | Total | MAF | AA | AG | GG | Total | MAF | |||
England/Wales | 1 | 39 | 3626 | 3666 | 0.0056 | 0 | 72 | 6068 | 6140 | 0.0059 | 0.93 (0.64 to 1.36) | .71 |
Scotland | 0 | 21 | 2031 | 2052 | 0.0051 | 0 | 23 | 1981 | 2004 | 0.0057 | 0.90 (0.52 to 1.56) | .72 |
Holland | 0 | 6 | 405 | 411 | 0.0073 | 0 | 5 | 384 | 389 | 0.0064 | 1.07 (0.43 to 2.64) | .89 |
Spain | 0 | 4 | 272 | 276 | 0.0072 | 0 | 5 | 279 | 284 | 0.0088 | 0.91 (0.35 to 2.38) | .84 |
Portugal | 0 | 4 | 195 | 199 | 0.0101 | 0 | 6 | 180 | 186 | 0.0161 | 0.75 (0.29 to 1.95) | .56 |
Germany | 0 | 3 | 249 | 252 | 0.0060 | 0 | 16 | 1071 | 1087 | 0.0074 | 1.17 (0.47 to 2.92) | .74 |
Combined | 1 | 77 | 6778 | 6856 | 0.0058 | 0 | 127 | 9963 | 10090 | 0.0063 | 0.94 (0.72 to 1.21) | .61 |
* Odds ratios and P values were generated using logistic regression. For the combined analysis, odds ratio and P value shown are from fixed-effects meta-analysis.