Table 3.
Stenosis and procedural characteristics (per optimization subgroup)
| PCI optimization without change based on OCT | PCI optimization based on Pre-PCI OCT only | PCI optimization based on post-PCI OCT only | PCI optimization based on pre-PCI and post-PCI OCT | P-value* | ||
|---|---|---|---|---|---|---|
| Stenoses | n | 146 | 185 | 46 | 79 | |
| Planned number of stents prior to OCT | Mean ± SD | 1.1 ± 0.37 | 1.14 ± 0.41 | 1.17 ± 0.44 | 1.22 ± 0.41 | 0.293 |
| Actual number of stents per patient | Mean ± SD | 1.17 ± 0.41 | 1.22 ± 0.47 | 1.32 ± 0.57 | 1.49 ± 0.75 | 0.0004 |
| Pre-PCI % stenosisa | Mean ± SD | 64.2 ± 16.1 | 64.5 ± 17 | 69.1 ± 20 | 59.5 ± 17.5 | 0.159 |
| Post-PCI % stenosisa | Mean ± SD | 13.6 ± 16 | 14.4 ± 12.7 | 22.3 ± 14.7 | 22.3 ± 19.7 | 0.007 |
| Pre-PCI FFR | Mean ± SD | 0.72 ± 0.14 | 0.73 ± 0.14 | 0.72 ± 0.14 | 0.72 ± 0.13 | 0.931 |
| Post-PCI FFR | Mean ± SD | 0.89 ± 0.07 | 0.89 ± 0.07 | 0.89 ± 0.08 | 0.86 ± 0.09 | 0.0035 |
| Final FFR | Mean ± SD | — | — | 0.9 ± 0.1 | 0.9 ± 0.1 | 0.2417 |
| Pre-PCI MLAb | Mean ± SD | 1.9 ± 1.2 | 1.7 ± 0.8 | 1.6 ± 0.9 | 1.8 ± 0.8 | 0.113 |
| Post-PCI MLAb | Mean ± SD | 6.1 ± 2.5 | 5.2 ± 2.1 | 5.3 ± 1.8 | 5.0 ± 2.0 | 0.004 |
| Fluoroscopy duration | min | 21 ± 14.7 | 25.7 ± 35.2 | 23.9 ± 13.1 | 31.9 ± 25.7 | 0.0536 |
| Procedure duration | min | 87.6 ± 37 | 89.7 ± 34.9 | 93.6 ± 26.1 | 106.4 ± 39.5 | 0.0043 |
| Contrast agent used | mL | 275.5 ± 127.6 | 260.7 ± 122 | 251.8 ± 132 | 256.3 ± 124.5 | 0.6012 |
*Continuous and categorical P-values were calculated using an ANOVA F-test and Fishers Exact MCMC statistics, respectively.
FFR, fractional flow reserve; OCT, optical coherence tomography; PCI, percutaneous coronary intervention.
apercent diameter stenosis by OCT (%).
bMLA, minimal luminal area by OCT (mm2).