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. 2015 Dec 14;5:18110. doi: 10.1038/srep18110

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(a) Changes of trans-epithelial current after Ba²⁺ (1 mM) application. (b) Dose-dependent changes of trans-epithelial current after various concentrations of Ba²⁺. (c) Inhibition of the K⁺ secretion current after 4-AP (10 mM) application. (d) Larger effect of the simultaneous application of 4-AP (10 mM) and Ba²⁺ (1 mM) than that of 4-AP (10 mM) alone on the trans-epithelial current. (e) Representative figure for the changes of trans-epithelial current after apamin (100 nM) application. (f) Comparison of the mean basal current, changes in the current after the application of K⁺ channel blockers, and the absolute amount of current density change according to the K⁺ blockers that were used. The changes in the current density after the application of Ba²⁺ (1 mM) and 4-AP (10 mM) were greater than the amount of basal current. Values are means ± SE. All figures except for Figures b and e show the averages of all experiments; SE is drawn only at intervals for clarity in Figures a, c, and d. *p < 0.05.